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Apr 20, 2024
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CHE 550 - Enzymology Background in enzyme structure-function and the skills necessary to critically interpret kinetic studies and X-ray crystallographic experiments. Topics include steady-state and transient kinetics, crystal growth, diffraction, phasing and refinement to determine structure. Prerequisite: CHE 451 or graduate standing. (3 cr. hr.)
Frequency code C = offered at least once every two years
Student Learning Outcomes
Upon successful completion of this course, students will be able to:
- Critically analyze and evaluate protein X-ray crystallographic data, including data collection and refinement statistics.
- Apply the results of enzymatic kinetic data to analyze chemical mechanisms and inhibitor design.
- Determine the relationships between the structure of an enzyme and its function using 3-dimensional molecular visualization.
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